ALEXA logo and images of BC Cancer Agency
Button link to homepage of the ALEXA-Seq website Button link to an introduction to the ALEXA-Seq website Button link to detailed methods for how ALEXA-Seq is used to study alternative transcript expression Button link to results for a validation experiment using the ALEXA-Seq approach Button link to the download area for supplementary data and source code
List of recent events pertaining to the ALEXA custom microarray design resource Welcome to the ALEXA platform banner

Intro: A brief introduction to alternative expression analysis by massively parallel RNA sequencing

Methods: A brief overview of the methods employed in this analysis.

Results: Visualize alternative expression in one of 19 data sets with the ALEXA-Seq data viewer.

Downloads: Get ALEXA-Seq annotation databases for eight species, raw data, source code, etc.

ALEXA-Seq is a method for using massively parallel paired-end transcriptome sequencing for 'alternative expression analysis'.

Citation: Malachi Griffith, Griffith OL, Mwenifumbo J, Morin RD, Goya R, Tang MJ, Hou YC, Pugh TJ, Robertson G, Chittaranjan S, Ally A, Asano JK, Chan SY, Li I, McDonald H, Teague K, Zhao Y, Zeng T, Delaney AD, Hirst M, Morin GB, Jones SJM, Tai IT, Marco A. Marra. Alternative expression analysis by RNA sequencing. Nature Methods. 2010 Oct;7(10):843-847. Pubmed | Full text | PDF | Supplementary Information | GEO (GSE23776) | News and Views | Press Release

List of data sets Gene search

Additional projects are being analyzed externally at the LBL Life Sciences Division: alexa-seq-lbl.org the Washington University School of Medicine - Genome Insitute: WASHU alexa-seq
Button link to main ALEXA home page Button link to ALEXA-Arrays home page Button link to ALEXA-Seq home page Button link to acknowledgements of funding and other support for Malachi Griffith and Marco Marra Button link to contact information for Malachi Griffith and Marco Marra